

Monthly 5-in-1 Spot-On for Heartworm, Fleas and Parasites in Large Cats
Product Description
Parasedge Multi for Cats (Purple Box) is an FDA-approved, prescription-only monthly spot-on for cats and kittens 9 weeks or older weighing 9.1 to 18 lbs. Each 0.8 mL tube contains 10% imidacloprid and 1% moxidectin, delivering broad-spectrum 5-in-1 protection. It prevents heartworm disease, kills adult fleas, treats flea infestations, ear mites, and intestinal roundworm and hookworm infections in one monthly application.
Benefits
- Prevents Heartworm Disease: Moxidectin prevents Dirofilaria immitis larval development into adult heartworms when applied once monthly to large cats.
- Kills Adult Fleas: Imidacloprid kills adult Ctenocephalides felis fleas and treats flea infestations, providing rapid flea relief with each monthly dose.
- Treats Ear Mite Infestations: Treats and controls Otodectes cynotis ear mite infestations in cats and kittens with each monthly topical application.
- Treats Roundworms: Treats and controls Toxocara cati intestinal roundworm infections in cats with each monthly dose.
- Treats Hookworms: Treats and controls Ancylostoma tubaeforme intestinal hookworm infections in cats with each monthly dose.
- Same Ingredients as Advantage Multi: Contains the same 10% imidacloprid and 1% moxidectin combination as Advantage Multi for Cats, offering equivalent protection.
- Approved for Ferrets (0.4 mL only): The 0.4 mL Orange Box tube is the only Parasedge Multi size approved for heartworm prevention and flea treatment in ferrets.
Ingredients
Composition Table
| Ingredient | Quantity |
| Imidacloprid | 10% (80 mg per 0.8 mL tube) |
| Moxidectin | 1% (8 mg per 0.8 mL tube) |
Other Ingredients
Benzyl alcohol, Propylene carbonate
How to Use
Directions for Use
- Prescription Required: US federal regulations require that a licensed veterinarian either prescribe or oversee the use of this medication.
- Minimum Dose: Apply to the skin once every month, with each dose supplying at least 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin.
- Open Foil Pack With Scissors: Use scissors to carefully open the foil pack to avoid damaging the tube; remove and hold upright with lot and expiry at the bottom.
- Snap or Cut the Tip: Bend the tip backward firmly until it snaps off; if it does not snap, use scissors to cut it open.
- Apply at Base of Head: Part the fur at the back of the neck, place the tube tip on the exposed skin, and squeeze the entire contents onto the skin.
- Do Not Apply to Irritated Skin: Never apply to broken or irritated skin; always select a healthy, intact area of skin for each application.
- Apply Once Monthly Year-Round: Administer every 30 days, year-round, for continuous heartworm prevention and complete parasite protection.
- Prevent Licking for 30 Minutes: Keep the cat from licking the treated area for at least 30 minutes, and separate pets in homes with multiple animals until it is dry.
- Test for Heartworm Before Starting: All cats should be tested for existing heartworm disease before beginning a heartworm prevention protocol with Parasedge Multi.
Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.
Additional Information
Precautions
- Minimum Age and Weight: Do not use on cats less than 9 weeks of age or under 2 lbs; use only the Purple Box for cats weighing 9.1 to 18 lbs.
- Sick or Debilitated Cats: Never apply Parasedge Multi to sick, debilitated, or underweight cats regardless of their age or current body weight.
- Geriatric Cats: Safety in geriatric cats with subclinical conditions has not been established; consult your veterinarian before use in older cats.
- Breeding, Pregnant, and Lactating Cats: Safety has not been established in breeding, pregnant, or lactating cats; always consult your veterinarian before use.
- Purple Box Not for Ferrets: Only the 0.4 mL Orange Box is approved for ferrets; using the 0.8 mL Purple Box could cause a serious moxidectin overdose.
- Licking Prevention Critical: Accidental ingestion or licking of the application site may cause hypersalivation, tremors, vomiting, and decreased appetite in cats.
- Keep Children Away: Children should not come into contact with the application site for at least 30 minutes after product application.
- Eye Irritant for Handlers: This product causes eye irritation in humans; wash hands thoroughly after handling and flush eyes with water if contact occurs.
Possible Side Effects
- Hypersalivation: Excessive drooling may occur if the cat grooms the application site; applying at the base of the head minimizes licking risk.
- Vomiting and Decreased Appetite: Vomiting and reduced appetite have been reported when the product is accidentally ingested through self-grooming.
- Tremors: Neurological tremors have been reported following accidental ingestion of the product; contact your veterinarian immediately if observed.
- Application Site Reactions: Stiff, matted hair, redness, or an oily appearance at the application site may occur; this is a temporary cosmetic effect only.
- Human Adverse Reactions: Human exposure may cause headache, dizziness, and skin redness, burning, tingling, or numbness; seek medical attention if these occur.
Storage Information
- Store at Controlled Temperature: Store between 4°C (39°F) and 25°C (77°F) and avoid exposure to excess heat or cold.
- Keep in Original Foil Packaging: Store tubes in the original sealed foil pouch until immediately before use to protect from moisture.
- Keep Away from Children and Pets: Store this prescription product securely out of reach of children and other animals at all times.
Shipping & Return
We offer ground, express, and priority delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: What does Parasedge Multi for Cats (Purple Box) treat and prevent?
Ans: Parasedge Multi for large cats is a once-monthly 5-in-1 topical solution. It prevents heartworm disease, kills adult fleas, treats flea infestations, controls ear mites, and treats intestinal roundworm and hookworm infections. It is approved for cats and kittens 9 weeks or older weighing 9.1 to 18 lbs.
Q2: How does Parasedge Multi for Cats differ from Advantage Multi for Cats?
Ans: Both products contain identical active ingredients — 10% imidacloprid and 1% moxidectin — at the same concentrations, providing the same 5-in-1 parasite protection. The primary difference is the brand and manufacturer. Parasedge Multi offers equivalent therapeutic coverage as a more affordably priced alternative.
Q3: How does the Purple Box differ from the Orange Box?
Ans: The Purple Box contains 0.8 mL per tube delivering 80 mg imidacloprid and 8 mg moxidectin for large cats. The Orange Box contains 0.4 mL per tube for medium cats and is also approved for ferrets. The Purple Box must never be used in ferrets due to moxidectin overdose risk.
Q4: Why is the Purple Box not approved for ferrets?
Ans: The 0.8 mL Purple Box delivers more than double the appropriate moxidectin dose for a ferret, risking serious overdose. Only the 0.4 mL Orange Box is approved for ferrets at the correct minimum dose. Effectiveness in ferrets over 4.4 lbs has also not been established.
Q5: Is Parasedge Multi safe for breeding, pregnant, or lactating large cats?
Ans: The safety of Parasedge Multi has not been established in breeding, pregnant, or lactating cats. Before starting parasite prevention program, consult a veterinarian if your cat is pregnant, lactating, or being used for breeding.
Q6: My large cat weighs more than 18 lbs. Can I still use Parasedge Multi?
Ans: Yes. For cats over 18 lbs, an appropriate combination of available Parasedge Multi tube sizes should be used to achieve the correct dose. Never rely on a single Purple Box tube alone. Always confirm the correct tube combination with your veterinarian before applying.
Clinical Research
Imidacloprid: Insecticide Overview – National Pesticide Information Center (NPIC)
Moxidectin: Pharmacological Profile – Wikipedia
Heartworm Disease Guidelines – American Heartworm Society
Year-Round Flea & Tick Prevention – Companion Animal Parasite Council (CAPC)
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